Googling the cancer genome
Identification and prioritization of cancer-causing structural variations in patient-derived whole genome sequencing data
A portable and scalable bioinformatics workflow for detecting structural variants in whole-genome sequencing data.
This Snakemake-based workflow combines several state-of-the-art tools (i.e. Manta, DELLY, LUMPY and GRIDSS) for detecting structural variants (SVs) in whole genome sequencing data. The workflow is easy to use and to deploy on any Linux-based machine. In particular, the workflow supports automated software deployment, easy configuration and addition of new analysis tools as well as enables to scale from a single computer to different HPC clusters with minimal effort.